Resumo Um problema de preocupação mundial são as altas taxas de abandono dos estudos universitários. Buscando respostas para esse fenômeno, este estudo apresenta um modelo preditivo sobre o nível de adaptabilidade de estudantes do Ensino Médio com intenção de cursar estudos universitários. O objetivo é mostrar as relações existentes entre as três variáveis exógenas (competências para o estudo, informações sobre a universidade e expectativas de autoeficácia) e a variável endógena (adaptabilidade) consideradas no modelo. Participou deste trabalho uma amostra de 290 alunos do Ensino Médio que manifestaram a intenção de cursas estudos universitários. Os resultados indicam uma relação substancial e consistente entre as variáveis do modelo, ajudando a predizer os níveis de adaptabilidade acadêmica dos estudantes do Ensino Médio com intenção de cursar estudos universitários. O resultado é interessante para desenhar propostas norteadoras para as etapas anteriores à universidade.

Abstract High rates of dropout from university are a worldwide concern. In an attempt to address this phenomenon, this study presents a predictive model for the level of adaptability of high school students intending to pursue a university education. The objective is to show the relationships existing between the three exogenous variables (study skills, information about the university, and self-efficacy expectations) and the endogenous variable (adaptability) included in the model. The study involved a sample of 290 high school students who had expressed their intention to pursue a university education. The results show a substantial and consistent relationship between the variables of the model, helping to predict the levels of academic adaptability of high school students planning to attend university. This is of interest in designing guidance for pre-university stages of education.

Resumen Un problema que preocupa a nivel mundial son las elevadas cifras de abandono de los estudios universitarios. Buscando respuestas a este fenómeno, en este estudio se presenta un modelo predictivo sobre el nivel de adaptabilidad del alumnado de bachillerato con intención de cursar estudios universitarios. El objetivo es mostrar las relaciones existentes entre las tres variables exógenas (competencias para el estudio, información sobre la universidad y expectativas de autoeficacia) y la variable endógena (adaptabilidad) contempladas en el modelo. En el trabajo participó una muestra de 290 estudiantes de bachillerato que habían manifestado su intención de cursar estudios universitarios. Los resultados indican una relación sustancial y consistente entre las variables del modelo, ayudando a predecir los niveles de adaptabilidad académica de los estudiantes de bachillerato con intención de cursar estudios universitarios. Esto resulta de interés para diseñar propuestas orientadoras para las etapas previas a la universidad.

ABSTRACT BACKGROUND: Psoriatic arthritis (PsA) is a chronic inflammatory disease that affects multiple joints. It is associated with psoriasis and treated with synthetic and biologic drugs. OBJECTIVE: The objective of this study was to assess the outcomes of patients who received biologic therapy with tumor necrosis factor (TNF) inhibitors in terms of effectiveness, safety, functionality, and quality of life. DESIGN AND SETTING: A prospective observational study was performed at a single center in Belo Horizonte, Brazil. METHODS: Patients with PsA who received their first TNF inhibitor treatment were followed up for 12 months. Disease activity was measured using the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and Clinical Disease Activity Index (CDAI). Functionality was measured using the Health Questionnaire Assessment (HAQ), and quality of life was evaluated using the European Quality of Life Five Dimensions (EQ-5D). Multiple linear regression was used to identify predictors of the clinical response at 12 months. RESULTS: A total of 143 patients treated with adalimumab or etanercept were evaluated. Most of the clinical measures were significantly improved at 12 months. However, 31%–51% of the patients did not achieve good clinical control. No differences were observed between adalimumab and etanercept, except for poor functionality at 12 months among patients treated with etanercept. The main predictors of a worse clinical response were female sex, etanercept use, poor functionality, or lower quality of life at baseline. The main adverse reactions were alopecia, headache, injection site reaction, sinusitis, flu, dyslipidemia, and infections. CONCLUSION: TNF inhibitor therapy was effective and safe. However, despite improvements in clinical measures, most patients did not achieve satisfactory control of the disease.

Resumo A segurança do paciente é uma dimensão essencial da qualidade dos cuidados de enfermagem. É um dever dos enfermeiros e um objetivo das organizações de saúde. O objetivo deste artigo é analisar a evidência científica acerca da segurança do paciente em hospital - serviço de urgência, na opinião dos enfermeiros. Trata-se de uma revisão sistemática da literatura com três etapas. 1) Pesquisa inicial nas bases CINAHL e MEDLINE. 2) Pesquisa mais alargada, nas restantes bases de dados da plataforma EBSCOHost. 3) Pesquisa nas referências bibliográficas dos artigos selecionados. Os estudos selecionados compreendem o período entre 2014 e 2019, resultando em cinco artigos. Os enfermeiros consideram que o ambiente de prática de enfermagem, o trabalho em equipa e as questões relacionadas com a liderança dos enfermeiros gerentes são fatores fundamentais para se melhorar a qualidade dos cuidados prestados e a segurança do paciente. Incentivar o trabalho em equipa melhora a assistência ao paciente, reduz os eventos adversos e incrementa a qualidade. Conhecer a opinião dos enfermeiros sobre a segurança do paciente nos serviços de urgência contribui para melhorar a qualidade dos cuidados de enfermagem.

Abstract Patient safety in health care is the cornerstone of quality in nursing care. It is a duty of nurses and an objective of the health organizations. This article aims to analyze the scientific evidence on the nurses’ perception and opinion on patient safety in the emergency department. Systematic literature review with 3 steps. 1) Primary search at CINHAL and MEDLINE. 2) A broader search, using the same keywords and search terms in the remaining database of the EBSCOHost platform. 3) Search the bibliographic references of the selected articles. The selected studies were published between 2014 and 2019. Five articles were selected. The nurses’ perception reveal that the work environment, teamwork and matters related to the leadership of hierarchical superiors are fundamental factors to improve the quality of care provided and patient safety. Promoting teamwork improves patient care, reduces adverse events and improves quality. Recognizing the nurses’ perception on patient safety culture in emergency services, contributes to improving the quality of care provided.

Resumo A segurança do paciente é uma dimensão essencial da qualidade dos cuidados de enfermagem. É um dever dos enfermeiros e um objetivo das organizações de saúde. O objetivo deste artigo é analisar a evidência científica acerca da segurança do paciente em hospital - serviço de urgência, na opinião dos enfermeiros. Trata-se de uma revisão sistemática da literatura com três etapas. 1) Pesquisa inicial nas bases CINAHL e MEDLINE. 2) Pesquisa mais alargada, nas restantes bases de dados da plataforma EBSCOHost. 3) Pesquisa nas referências bibliográficas dos artigos selecionados. Os estudos selecionados compreendem o período entre 2014 e 2019, resultando em cinco artigos. Os enfermeiros consideram que o ambiente de prática de enfermagem, o trabalho em equipa e as questões relacionadas com a liderança dos enfermeiros gerentes são fatores fundamentais para se melhorar a qualidade dos cuidados prestados e a segurança do paciente. Incentivar o trabalho em equipa melhora a assistência ao paciente, reduz os eventos adversos e incrementa a qualidade. Conhecer a opinião dos enfermeiros sobre a segurança do paciente nos serviços de urgência contribui para melhorar a qualidade dos cuidados de enfermagem.

Abstract Patient safety in health care is the cornerstone of quality in nursing care. It is a duty of nurses and an objective of the health organizations. This article aims to analyze the scientific evidence on the nurses’ perception and opinion on patient safety in the emergency department. Systematic literature review with 3 steps. 1) Primary search at CINHAL and MEDLINE. 2) A broader search, using the same keywords and search terms in the remaining database of the EBSCOHost platform. 3) Search the bibliographic references of the selected articles. The selected studies were published between 2014 and 2019. Five articles were selected. The nurses’ perception reveal that the work environment, teamwork and matters related to the leadership of hierarchical superiors are fundamental factors to improve the quality of care provided and patient safety. Promoting teamwork improves patient care, reduces adverse events and improves quality. Recognizing the nurses’ perception on patient safety culture in emergency services, contributes to improving the quality of care provided.

ABSTRACT Introduction: kidney cancer represents 2 % of genitourinary neoplasms; it is usually diagnosed between the fourth and sixth decade of life. Objective: to characterize the clinical-epidemiological behavior and therapeutic management of renal cell carcinoma in Pinar del Rio during 2016-2019. Methods: a descriptive, retrospective study was conducted in Pinar del Rio from 2016 to 2019, with a target group of 26 patients treated by renal cancer surgery and a sample comprising 21 patients who attended the Oncology Care Center (III Congreso). Clinical history information was collected: age, gender and skin color, symptoms at diagnosis, affected kidney, clinical stages, histology and treatment. A database was prepared where qualitative variables were expressed in absolute frequencies and relative frequencies in percentages. Results: there was a predominance in the age bracket 70 years and over with 8 patients (33,3 %), most of them asymptomatic 12 (60 %), with a greater involvement of the left kidney 15 (71,4 %) and 7 (33,3 %) in the middle part. Histologically corresponding to the clear cell type 16 (76,2 %), diagnosed 15 (71,4 %) in stage I, with total nephrectomy 20 (95,2 %). Conclusions: renal cancer predominated in the eighth decade of life, male, asymptomatic at diagnosis, with more involvement of the left kidney in the middle part. Histologically corresponding to clear cells with nuclear grade II, without vascular or lymphatic invasion or thrombi in the renal vein, diagnosed in stage I, mostly treated with total nephrectomy.

RESUMEN Introducción: el cáncer de riñón representa el 2 % de las neoplasias genitourinarias, habitualmente se diagnostican entre la cuarta y la sexta década de la vida. Objetivo: caracterizar el comportamiento clínico-epidemiológico, y manejo terapéutico del carcinoma de células renales en Pinar del Río entre el 2016-2019. Métodos: se realizó un estudio descriptivo, retrospectivo en Pinar del Río desde el 2016 al 2019, con un universo de 26 pacientes tratados por cirugía de cáncer renal y una muestra constituida por 21 pacientes atendidos en el Centro de atención Oncológico (III Congreso). Se recolectó la información de la historia clínica: edad, género y color de la piel, síntomas al diagnóstico, riñón afecto, etapas clínicas, histología y tratamiento. Se confeccionó una base de datos donde las variables cualitativas se expresaron en frecuencias absolutas y las relativas en porcientos. Resultados: hubo un predominio en el grupo de 70 años y más con ocho pacientes (33,3 %), en mayoría asintomáticos 12 (60 %), mayor afección del riñón izquierdo 15 (71,4 %) en parte media siete (33,3 %). Histológicamente, según el tipo de células claras 16 (76,2 %), diagnosticados 15 (71,4 %) en etapa I, con nefrectomía total 20 (95,2 %). Conclusiones: el cáncer renal predominó en la octava década de la vida, masculinos, asintomáticos al diagnóstico, más afección del riñón izquierdo en parte media. Histológicamente de acuerdo a células claras con grado nuclear II, sin invasión vascular ni linfática ni trombos en la vena renal, diagnosticados en etapa I, tratados con nefrectomía total en su mayoría.

ABSTRACT Introduction: among the neoplasms affecting males, testicular germ cell tumors account for 0,5-1 %. In the last four decades there has been an increase in the incidence of testicular cancer from 5,7 to 6,8 cases per 100,000 inhabitants. Objective: to characterize the epidemiological clinical behavior and therapeutic management of patients with testicular cancer in Pinar del Rio from 2010 to 2019. Methods: an observational, descriptive, retrospective study was carried out in Pinar del Río province from 2010 to 2019 which comprised the total number of patients diagnosed and treated for testicular cancer registered in the Cancer Care Center (III Congress). A data base was made where qualitative variables were expressed in absolute frequencies and relative frequencies in percentages. Results: ages between 31 and 40 predominated (29,5 %) and white race (94,1 %); the most frequent reason for consultation was testicular enlargement (70,6 %). Histologically, seminoma predominated (58,8 %), with predominance of clinical stages IA and IB. There was a stable disease response in 41,2 %. Conclusions: testicular tumors occurred more frequently in the fourth decade of life attending consultation for testicular enlargement; the most frequent histological type were seminomas in clinical stages IA and IB and in most of them there was a stable response of the disease.

RESUMEN Introducción: dentro de las neoplasias que afectan al varón se encuentran los tumores germinales testiculares, constituyen entre el 0,5-1 %. En las cuatro últimas décadas se ha percibido un aumento en la incidencia del cáncer testicular de 5,7 a 6,8 casos por cada 100 000 habitantes. Objetivo: caracterizar el comportamiento clínico epidemiológico y el manejo terapéutico del paciente con cáncer de testículo en Pinar del Río del 2010 al 2019. Métodos: se realizó un estudio observacional, descriptivo, retrospectivo en la provincia de Pinar del Río del 2010 al 2019, el cual estuvo constituido por el total de pacientes diagnosticados, tratados por cáncer de testículo registrados en el Centro de Atención al paciente Oncológico (III Congreso). Se confeccionó una base de datos donde las variables cualitativas se expresaron en frecuencias absolutas y las relativas en porcientos. Resultados: hubo un predominio entre 31 a 40 años de edad (29,5 %) y de la raza blanca (94,1 %); el motivo de consulta más frecuente fue el aumento de volumen testicular (70,6 %). Histológicamente predominaron los seminoma (58,8 %), con predominio de etapas clínicas IA y IB. Hubo una respuesta de enfermedad estable en el 41,2 %. Conclusiones: los tumores de testículos se presentaron con mayor frecuencia en la cuarta década de la vida donde se asiste a consulta por aumento de volumen testicular; el tipo histológico más frecuente fueron los seminomas en las etapas clínicas IA y IB y en la mayor parte hubo respuesta de enfermedad estable.

Resumo O objetivo desste trabalho foi estabelecer, por meio de diferentes métodos diagnósticos, valores de referência nutricional para bananeira ‘Prata-Anã’ em solo de fertilidade construída. O estudo contemplou um banco de dados de um experimento no delineamento em blocos casualizados, arranjado no esquema fatorial 5 × 6 (cinco doses de K2O - 0; 200; 400; 600 e 800 kg ha-1, supridas com esterco bovino e farinha de rocha × seis avaliações da nutrição foliar e produtividade - 210; 390; 570; 750; 930 e 1.110 dias após plantio), com três repetições, totalizando 90 amostras. Os valores de referência foram determinados pelos métodos da Faixa de suficiência, do Nível crítico pela distribuição normal reduzida, da Linha de fronteira, e pela Chance Matemática. Parcelas de alta produtividade, = 36,42 t ha-1 ciclo-1, formaram a população de referência e = 45,79 t ha-1 subpopulação de referência. Os métodos foram eficientes na determinação dos valores de referência nutricional da bananeira ‘Prata-Anã’. Os valores estabelecidos de forma geral são mais altos comparados à literatura, justificados pela maior fertilidade química do solo. Dentre os métodos diagnósticos, a Chance Matemática apresentou-se como o mais preciso para a interpretação dos teores de nutrientes nas folhas da bananeira ‘Prata-Anã’ em condições de fertilidade de solo construída.

Abstract The objective of this work was to establish, through different diagnostic methods, nutrient reference values for ‘Prata-Anã’ banana in improved fertility soil. The study included a database from an experiment conducted in randomized block design, arranged in a 5 × 6 factorial scheme (five doses of K2O - 0; 200; 400; 600 and 800 kg ha-1, supplied by cattle manure and rock powder × six evaluations of leaf nutrition and yield – 210; 390; 570; 750; 930 and 1,110 days after planting), with three replicates, totaling 90 samples. The reference values were determined by the Sufficiency Range, Critical Level by the Reduced Normal Distribution, Boundary Line and Mathematical Chance methods. Plots with high yield, = 36.42 t ha-1 cycle-1, formed the reference population and plots with yield = 45.79 t ha-1 formed the reference subpopulation. The methods were efficient in determining the nutrient reference values of ‘Prata-Anã’ banana. In general, the values established are higher than those reported in the literature, justified by the greater chemical fertility of the soil. Among the diagnostic methods, the Mathematical Chance presented itself as the most accurate for interpreting the nutrient contents in the leaves of ‘Prata-Anã’ banana under improved soil fertility conditions.

RESUMO Valores de referência dos teores foliares são essenciais para avaliação nutricional das plantas. Objetivou-se estabelecer valores de referência nutricional para a bananeira ‘BRS Platina’ em solo de fertilidade construída, mediante a utilização dos métodos faixa de suficiência (SR), linha de fronteira (BL) e chance matemática (MCh), além do nível crítico obtido pela distribuição normal reduzida (CLz). O estudo foi realizado em Guanambi-BA, considerando teores de nutrientes e produtividades de experimento arranjado em blocos casualizados, esquema fatorial 5 x 6, cinco doses de K2O (0, 200, 400, 600 e 800 kg ha-1) supridas com fertilizantes para manejo orgânico e seis épocas de amostragem (210; 390; 570; 750; 930 e 1.110 dias após plantio), totalizando 90 parcelas. Parcelas de alta produtividade, ≥ 38,40 t ha-1 formaram a população de referência e ≥ 47,43 t ha-1 subpopulação de referência. Houve convergência entre os valores ótimos obtidos pelos métodos avaliados. Portanto, os valores de referência ajustados pelos métodos SR, BL, MCh e CLz podem ser usados com assertividade para interpretação da análise foliar da bananeira ‘BRS Platina’ em solos de fertilidade construída. Ademais, dentre esses, a MCh se destaca pois proporciona faixas ótimas mais estreitas.

ABSTRACT Reference values of leaf nutrient contents are essential for nutritional assessment of plants. The objective was to establish nutritional reference values for ‘BRS Platina’ banana in improved fertility soil, using the sufficiency range (SR), border Line (BL) and mathematical chance (MCh) methods, in addition to the critical level obtained by the reduced normal distribution (CLz). The study was carried out in Guanambi-BA, considering nutrient contents and yields of an experiment arranged in randomized blocks, 5 x 6 factorial scheme, with five doses of K2O (0, 200, 400, 600 and 800 kg ha-1) supplied with fertilizers for organic management and six sampling times (210; 390; 570; 750; 930 and 1,110 days after planting), totaling 90 plots. Plots with high yield, ≥ 38.40 t ha-1, formed the reference population and plots with yield ≥ 47.43 t ha-1 formed the reference subpopulation. There was convergence between the optimal values obtained by the methods evaluated. Therefore, the reference values adjusted by the SR, BL, MCh and CLz methods can be used with assertiveness to interpret the foliar analysis of the ‘BRS Platina’ banana in improved fertility soils. Furthermore, among these, MCh stands out as it provides narrower optimal ranges.

ABSTRACT Introduction: septic renal colic is produced by an obstructive calculus of the urinary tract which is complicated by the localization of germs in the urine retained in the urinary tract. Objective: to characterize the clinical, epidemiological behavior and therapeutic management of patients with septic renal colic in Pinar del Río, between 2016 and 2019. Methods: an observational, descriptive research was carried out, with a target group of 186 patients and the sample consisted of 124 patients. The following data were collected from the medical records: age, sex, causes and clinical forms of septic renal colic, as well as the treatment applied. A database was prepared where qualitative variables were expressed in absolute frequencies and the relative in percentages. Results: a predominance of patients in the fifth and third decade of life with 22,6 % and 21,0 % of patients respectively was found, 60,5 % of them were male. Renal lithiasis was the predominant cause in 89,5 % of patients, being febrile renal colic the most frequent clinical form. Most were treated with cephalosporin (96,8 %) and nitronidazole (95,2 %). Endoscopic surgery was performed in 69,9 % and percutaneous nephrostomy in 54,2 %. Conclusions: septic nephritic colic was more frequent in the fifth decade of life in male sex, being febrile renal colic the clinical form and lithiasis the most frequent cause, in most patients endoscopic surgery was used for its resolution applying cefazolin and nitronidazole as antimicrobials.

RESUMEN Introducción: el cólico renal séptico es producido por un cálculo obstructivo de la vía urinaria el cual se complica con la localización de gérmenes en la orina retenida en el tracto urinario Objetivo: caracterizar el comportamiento clínico, epidemiológico y manejo terapéutico de los pacientes con cólico renal séptico en Pinar del Río, entre 2016 y 2019. Método: se realizó una investigación observacional, descriptiva, con un universo de 186 pacientes, la muestra quedó conformada por 124 pacientes. Se recopilaron de las historias clínicas los datos siguientes: edad, sexo, causas y formas clínicas del cólico renal séptico, así como el tratamiento empleado. Se confeccionó una base de datos donde las variables cualitativas se expresaron en frecuencias absolutas y las relativas en porcientos. Resultados: se encontró predominio de la quinta y tercera década de vida con 22,6 % y 21,0 % de pacientes respectivamente, el 60,5 % correspondió al sexo masculino. El 89,5 % presentaron litiasis renal como causa predominante, el cólico renal febril fue la forma clínica más frecuente. La mayoría fue tratada con cefalosporinas (96,8 %) y nitronidazoles (95,2 %). Resolvieron mediante cirugía endoscópica el 69,9 % y dentro de esta, la nefrostomía percutánea con el 54,2 %. Conclusiones: el cólico nefrítico séptico fue más frecuente en la quinta década de la vida en el sexo masculino, el cólico renal febril fue la forma clínica y la litiasis como causa más frecuente, en la mayoría de los pacientes se empleó la cirugía endoscópica para su resolución con la aplicación de antimicrobianos cefazolinas y nitromidazol.

ABSTRACT Background: considering that work accidents constitute a large source of cost generation and that in Cuba there is an aging age distribution, health care for workers is a fundamental process in primary health care. Objective: to characterize occupational health care at the Juan José Apolinaire Pennine Polyclinic in Cienfuegos. Methods: descriptive, cross-sectional study carried out in 2018. The sample made up of workers from the Carlos Manuel de Céspedes Thermoelectric Plant, chosen by simple random sampling, and doctors and nurses from the polyclinic family, intentionally selected. To obtain the information, two instruments were used, one applied to health personnel, to identify knowledge about occupational health and the other to the workers of the selected company to determine perceived satisfaction with the care received. Results: in the professionals of the Juan José Apolinaire Pennini polyclinic in Cienfuegos, there is evidence of a lack of knowledge about occupational health, by not showing clarity about occupational risks, causes of work accidents, examinations to be carried out in the working population and criteria for declaring an occupational disease . In addition, the surveyed patients are moderately satisfied with the care received, mainly due to deficiencies in stability, need and comprehensiveness of care. Conclusion: the research results suggest that there is a relationship between the lack of knowledge about occupational health in polyclinic workers and the insufficient attention perceived by the surveyed patients.

RESUMEN Fundamento: considerando que los accidentes de trabajo constituyen cuantiosa fuente de generación de costos y que en Cuba existe una distribución etaria envejecida, la atención a la salud de los trabajadores es un proceso fundamental en la atención primaria de salud. Objetivo: caracterizar la atención a la salud ocupacional en el Policlínico Juan José Apolinaire Pennine de Cienfuegos. Métodos: e studio descriptivo, de corte transversal realizado en 2018. La muestra constituida por trabajadores de la Termoeléctrica Carlos Manuel de Céspedes, escogida por muestreo simple aleatorio y médicos y enfermeras de la familia del policlínico, seleccionados de forma intencional. Para obtener la información se utilizaron dos instrumentos, uno aplicado al personal de la salud, para identificar conocimiento sobre salud ocupacional y otro a los trabajadores de la empresa seleccionada para determinar satisfacción percibida con la atención recibida. Resultados: en los profesionales del policlínico Juan José Apolinaire Pennini de Cienfuegos, se evidencia falta de conocimiento sobre salud ocupacional, al no mostrar claridad sobre riesgos laborales, causas de accidentes de trabajo, exámenes a realizar en población trabajadora y criterios para declarar una enfermedad profesional. Además los pacientes encuestados se encuentran medianamente satisfechos con la atención recibida, fundamentalmente por deficiencias en estabilidad, necesidad e integralidad de la atención. Conclusión: los resultados de la investigación son sugerentes de que existe una relación entre la falta de conocimiento sobre salud ocupacional en trabajadores del policlínico y la insuficiente atención percibida por los pacientes encuestados.

Abstract The crisis caused by the COVID-19 pandemic has profoundly affected the educational system, due to the interruption of academic normality and the transition to virtual learning. The changes derived from this situation represent a risk for students' educational trajectories and their enrollment in school. In relation to this problem, the objective of this study is to analyze the effect of academic burnout on the intent to leave school, among a sample of 475 university students of differing classifications. The results show a positive correlation between burnout and the intent to leave school. The data should serve to implement preventive programs to reduce the effects of stress, facilitate adapting to the new reality, and prevent the problem of dropping out.

Resumen La crisis provocada por la pandemia de COVID-19 ha afectado profundamente al sistema educativo, debido a la interrupción de la normalidad académica y el tránsito a una enseñanza virtual. Los cambios derivados de esta situación ponen en riesgo las trayectorias formativas del alumnado y la permanencia en los estudios. En relación con esta problemática, el objetivo del estudio es analizar el efecto que el burnout académico tiene en las intenciones de abandono de los estudios en una muestra de 475 estudiantes de diferentes grados universitarios. Los resultados muestran una correlación positiva entre el burnout y la intención de abandono académico. Los datos aportados deben servir para poner en marcha programas preventivos que reduzcan el efecto del estrés, faciliten la adaptación a la nueva realidad y eviten el problema de la deserción.

ABSTRACT: The biotrophic fungus Hemileia vastatrix causes coffee leaf rust (CLR), one of the most devastating diseases in Coffea arabica . Coffee, like other plants, has developed effective mechanisms to recognize and respond to infections caused by pathogens. Plant resistance gene analogs (RGAs) have been identified in certain plants as candidates for resistance ( R ) genes or membrane receptors that activate the R genes. The RGAs identified in different plants possess conserved domains that play specific roles in the fight against pathogens. Despite the importance of RGAs, in coffee plants these genes and other molecular mechanisms of disease resistance are still unknown. This study aimed to sequence and characterize candidate genes from coffee plants with the potential for involvement in resistance to H. vastatrix . Sequencing was performed based on a library of bacterial artificial chromosomes (BAC) of the coffee clone ‘Híbrido de Timor’ (HdT) CIFC 832/2 and screened using a functional marker. Two RGAs, HdT_LRR_RLK1 and HdT_LRR_RLK2, containing the motif of leucine-rich repeat-like kinase (LRR-RLK) were identified. Based on the presence or absence of the HdT_LRR_RLK2 RGA in a number of differential coffee clones containing different combinations of the rust resistance gene, these RGAs did not correspond to any resistance gene already characterized (SH1-9). These genes were also analyzed using qPCR and demonstrated a major expression peak at 24 h after inoculation in both the compatible and incompatible interactions between coffee and H. vastatrix . These results are valuable information for breeding programs aimed at developing CLR-resistant cultivars, in addition to enabling a better understanding of the interactions between coffee and H. vastatrix .

Resumen Introducción: El liderazgo de los líderes de enfermería clínica es un tema de creciente importancia, ya que las enfermeras, como líderes, son la pieza fundamental para comunicarse con el equipo y lograr objetivos y resultados, como la calidad de la atención de enfermería, la seguridad de clientes e innovación en salud. Objetivos: Analizar la evidencia científica sobre la efectividad de las enfermeras en el desarrollo de habilidades asociadas con la práctica del líder clínico. Métodos: Revisión sistemática de la literatura con 3 pasos. 1) Una búsqueda inicial en CINHAL y MEDLINE. 2) Una búsqueda más amplia, usando las mismas palabras clave y términos de búsqueda, en las bases de datos restantes de la plataforma EBSCOHost. 3) Buscar las referencias bibliográficas de los artículos seleccionados. Los estudios seleccionados fueron del período entre 2010 y 2019. Resultados: Se seleccionaron doce artículos en diferentes contextos de la práctica clínica líder de enfermería. La mayoría de los hallazgos informados que relacionan la efectividad de los líderes clínicos de enfermería con mejoras claras en el rendimiento y, en consecuencia, una mejora en los resultados de la atención médica. Conclusiones: Las habilidades de la enfermera líder clínica son parte de una práctica avanzada, con mejores resultados que conducen a un aumento en la calidad de la atención de enfermería, la atención médica y un aumento en la seguridad del cliente.

Resumo Introdução: A liderança dos enfermeiros líderes clínicos é um tema em crescente importância, uma vez que os enfermeiros, enquanto líderes, são a peça fundamental para comunicar com a equipa e alcançarem objetivos e resultados, como a qualidade dos cuidados de enfermagem, a segurança dos clientes e a inovação em saúde. Objetivos: Analisar a evidência científica acerca da eficácia dos enfermeiros no desenvolvimento de competências associadas a prática de líder clínico. Métodos: Revisão sistemática da literatura com 3 etapas. 1) Uma pesquisa inicial na CINHAL e MEDLINE. 2) Uma pesquisa mais alargada, utilizando as mesmas palavras-chave e termos de pesquisa, nas restantes bases de dados da plataforma EBSCOHost. 3) Pesquisa nas referências bibliográficas dos artigos selecionados. Os estudos selecionados foram do período entre 2010 e 2019. Resultados: Selecionou-se doze artigos em diferentes contextos de prática do enfermeiro líder clínico. A maioria relatou dados que relacionam a eficácia dos enfermeiros líderes clínicos com claras melhorias do desempenho e consequentemente melhoria nos resultados dos cuidados em saúde. Conclusões: As competências do enfermeiro líder clínico inserem-se numa prática avançada, com melhores desempenhos que conduzem ao aumento da qualidade dos cuidados de enfermagem, dos cuidados de saúde e ao aumento da segurança do cliente.

Abstract Introduction: The leadership of clinical nurse leaders is a topic of increasing importance, since nurses, as leaders, are the fundamental piece to communicate with the team and achieve objectives and results, such as the quality of nursing care, the patient safety and health innovation. Objectives: To analyze the scientific evidence about the effectiveness of nurses in the development of skills associated with the practice of clinical leader. Methods: Systematic literature review with 3 steps. 1) An initial search at CINHAL and MEDLINE. 2) A broader search, using the same keywords and search terms, in the remaining databases of the EBSCO Host platform. 3) Search the bibliographic references of the selected articles. The selected studies were from the period between 2010 and 2019. Results: Twelve articles were selected in different contexts of clinical nurse leader practice. Most reported findings that relate the effectiveness of clinical nurse leaders with clear improvements in performance and, consequently, improvement in health care outcomes. Conclusions: The skills of the clinical nurse leader are part of an advanced practice, with better performances that lead to an increase in the quality of nursing care, health care and an increase in patient safety.

Abstract Epigenetics studies focused on SARS-CoV-2 infection to assist in the perception of pathophysiology can direct prospective approaches for the COVID-19 treatment. There is an intrinsic relationship between epigenetic marks and the adaptation of the immune system, which determines the outcome of the pathogen-host interaction. Recently, studies have shown that there is an increased expression of the ACE2 receptor in individuals with Lupus, the origin of this phenomenon is from DNA’s methylation deregulation process that consequently, become this group more suitable to be infected by SARS-CoV-2. There is evidence for the use of some epigenetic modifiers known as Epidrugs, which might be a promising approach to be deeper investigated. Here we emphasize the importance of this glance upon Epigenetic and its modulators in the promising therapeutic in the COVID-19 disease context.